强直性 脊柱炎
Overview
强直性 spondylitis is an inflammatory condition that involves the spine and skeleton of the head and trunk. The disorder causes inflammation and pain in joints in the spine, pelvis and other parts of the skeleton. 除了, 部分脊柱, the hips or the sacroiliac joints where the hips join the lower back, 也许保险丝, 或成长, 在一起.
Our approach to ankylosing spondylitis
UCSF provides comprehensive evaluations and advanced care for ankylosing spondylitis. We offer the latest diagnostic techniques and strive to identify the disease early using special physical examination methods and magnetic resonance imaging (MRI).
Treatment options include nonsteroidal anti-inflammatory drugs and a class of medications called disease-modifying anti-rheumatic drugs, as well as newer medications that inhibit cytokines, immune system cells that appear to cause some of the 症状 of ankylosing spondylitis. 整形外科手术, such as joint replacement and spinal reconstruction, may be an option for patients with severe cases. We also recommend exercise and physical therapy to relieve pain and increase strength and flexibility.
除了 to caring for patients, our team conducts research to improve the understanding and treatment of ankylosing spondylitis. Interested patients may have the option to receive investigational treatments by participating in clinical trials.
奖 & 识别
-
Among the top hospitals in the nation
-
西部最好，排名第一. 7 in the nation for rheumatology
迹象 & 症状
Symptoms of ankylosing spondylitis include:
- 疼痛
- Stiffness, especially in the morning
- 功能限制
When the disorder affects the spine, it also may result in progressive deformity including curvature of the back, 叫驼背, and the inability to stand up straight.
诊断
The first clue in diagnosing ankylosing spondylitis is the presence of 症状, 尤其是背痛. 除了, X-rays are taken to look for signs of the disorder, such as fused joints. A blood test for the HLA-B27 gene, which is found in about 90 percent of the people with ankylosing spondylitis, 也可以执行. However, only 10 percent to 15 percent of people who inherit the gene develop ankylosing spondylitis.
治疗
强直性 spondylitis usually is treated with:
- 疼痛 or anti-inflammatory medications
- 治疗风湿病的药物
- 锻炼
- 物理治疗
Our experts are currently working with new medications that inhibit immune-system cells, 被称为细胞因子, which appear to cause some of the 症状 of ankylosing spondylitis.
关节置换手术, most commonly of the hips and shoulders, may be an option for severely affected patients. 除了, spinal reconstruction and internal bracing may be necessary to treat severe spine deformities associated with ankylosing spondylitis.
加州大学旧金山分校健康 medical specialists have reviewed this information. It is for educational purposes only and is not intended to replace the advice of your doctor or other health care provider. We encourage you to discuss any questions or concerns you may have with your provider.
